Health Risks Associated With a High BMI

Obesity has many negative effects on a person's health. It increases the risk of insulin resistance, diabetes, heart disease, and kidney disease. It also decreases a person's quality of life. Obese individuals are less likely to participate in physical activities and may face discrimination. You should need to use Diet calculator to know more about it.

Obesity increases risk of diabetes

People who are obese have a much higher risk of developing type 2 diabetes, also known as insulin-resistant diabetes or -onset diabetes. This disease is characterized by persistently high blood glucose levels. In fact, obese people are 80 times more likely to develop the disease than people with a BMI of 22 or less. This is because obesity causes fat cells to overprocess nutrients. This causes inflammation and releases cytokines that block insulin receptors.

People with high BMI are also more likely to develop diabetes. This is because excess abdominal fat releases pro-inflammatory chemicals that decrease the body's ability to respond to insulin. Insulin resistance is a hallmark of type 2 diabetes, and excess abdominal fat is referred to as central obesity.

Insulin resistance

Insulin resistance is a condition that results in an individual's body's inability to use insulin properly. This condition can lead to diabetes, hypertension, and dyslipidemia. It also increases the risk of other health problems. Fortunately, insulin resistance is a condition that can be treated. The key is to lose weight and improve insulin sensitivity. If you're overweight, start by talking to your doctor about your lifestyle.

Insulin resistance is linked to a high BMI and a high body fat percentage. However, assessing body fat percentage is not easy, and estimating body fat percentage requires a significant investment of time and equipment. Therefore, it may be more accurate and useful to assess insulin resistance based on a person's BMI alone without considering body fat percentage.

Kidney disease

In general, studies have shown that higher BMI is associated with higher risk of renal failure. So, follow BMI calculator to be updated with the risk. However, the results have been inconsistent. Some studies reported no association between higher BMI and ESRD, while others reported that high BMI is associated with a higher risk of proteinuria and hypertension.

These findings suggest that people with obesity and diabetes should have their kidneys tested more often. While there is no cure for chronic kidney disease, early detection and weight loss can help slow its progression. Researchers from the Medical Research Council-Kidney Research David Kerr Centre in the UK, William G. Herrington, said that "BMI seems to be a strong risk factor for both chronic kidney disease and diabetes."

Heart disease

People with a high BMI are at greater risk for developing heart disease. Studies have linked the high BMI to increased blood levels of interleukin 6 (IL-6) and interleukin-6 receptor (CRP), which are two key markers of heart disease. These two molecules increase the production of proteins and other compounds that form atherosclerotic plaques. High BMI also increases levels of lipids and glucose in the blood.

Several studies have linked high BMI to increased risk for cardiovascular disease, including coronary heart disease. These studies have also linked increased BMI with higher risk for non-ST segment elevation myocardial infarction, heart failure, and other cardiovascular diseases. Studies have shown that a ten-kilogram increase in BMI increases the risk for coronary heart disease by 12%.

Gallbladder disease

Gallbladder disease is an increasingly common condition, and high BMI is associated with an increased risk. Gallstones are pebble-like deposits in the gallbladder that can develop from excess cholesterol, bile salts, and bilirubin. In the United States alone, gallstone disease costs over $5 billion annually. While the cause of gallstone disease is not fully understood, studies suggest that a high BMI is associated with an increased risk.

In a study of almost 80,000 American men, researchers examined the association between anthropometric measurements and the risk of gallbladder disease. They used BMI as a proxy for risk and studied subjects' blood pressure and serum tests. The study included 7831 men of Japanese ancestry in Hawaii, and included 152,831 person-years of follow-up. During this time, 471 incident cases of gallbladder disease were diagnosed through radiology and histology. The study found that people with a high BMI had almost twice as much risk of gallbladder disease than those with a normal BMI.

Ovarian cancer

According to a new study, women with high BMIs have a higher risk of developing ovarian cancer than those with low BMIs. This association was revealed in a study published in Gynecologic Oncology. The researchers evaluated 21 case-control studies for association between BMI and survival. The researchers assessed the effects of obesity and BMI on overall survival, progression-free survival (PFS), and ovarian cancer-specific survival (OS) measures.


The researchers concluded that a high BMI increases the risk of ovarian cancer by approximately 15 percent. These results were consistent across all studies and included data from a total of 780,425 women. Interestingly, women with high BMIs were more likely to have invasive ovarian cancers than those with lower BMIs.